abstract：BACKGROUND:Low 25-Hydroxy-vitamin-D; "25(OH)-D3" serum and vitamin D receptor (VDR) levels were recently correlated to advanced fibrosis. However, VDR mechanism in liver fibrosis modulations is not well understood. In this study, we aimed to evaluate changes in liver NK cells cytotoxicity due to modulations in VDR in C...

journal_title：BMC gastroenterology

authors： Salhab A,Amer J,Yinying L,Safadi R

更新日期：2020-04-10 00:00:00

abstract：BACKGROUND:There are obviously ethnic differences between the UGT1A1 gene polymorphisms. Due to the difference of genetic background and environment, the treatment with colorectal cancer patients of Guangxi Zhuang should not completely follow the Euramerican or Chinese han patients. The study aimed to explore the corre...

journal_title：BMC gastroenterology

authors： Chen S,Hua L,Feng C,Mo Q,Wei M,Shen Y,Lin Z,Li G,Xu J,Guo C,Huang H

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:Endoscopic balloon dilation and/or plastic stent placement has been a standard method for treating biliary strictures complicated post living donor liver transplantation (LDLT). The strictures may be refractory to endoscopic treatment and require long-term stent placement. However, consensus on the optimal p...

journal_title：BMC gastroenterology

authors： Koizumi M,Kumagi T,Kuroda T,Imamura Y,Kanemitsu K,Ogawa K,Takada Y,Hiasa Y

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:Percutaneous Endoscopic Gastrostomy (PEG) feeding tubes are frequently placed in patients to provide enteral nutrition. We report a case of a complete rupture of a PEG tube intra-abdominally with associated peritonitis after more than a month of PEG placement and utilization. To our knowledge, this is a very...

journal_title：BMC gastroenterology

authors： Al Halabi M,Wakim W,Moukaddam H,Husari A

更新日期：2020-03-30 00:00:00

abstract：BACKGROUND:Pseudoachalasia is a rare disorder which has clinical, radiographic, and manometric findings that are often indistinguishable from primary achalasia. It is usually associated with malignancy. Few reports describe vascular compression as a cause of pseudoachalasia. CASE PRESENTATION:Here we present a case of...

journal_title：BMC gastroenterology

authors： Dejaeger M,Lormans M,Dejaeger E,Fagard K

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:Gastric tuberculosis mimicking submucosal tumors is extremely rare and often misdiagnosed. CASE PRESENTATION:Three cases of gastric tuberculosis mimicking submucosal tumors were identified among patients admitted to local county hospitals because of upper abdominal discomfort and pain, with gastroscopy show...

journal_title：BMC gastroenterology

authors： Zhu R,Zhou Y,Wang H,Di L,Zhao K,Tuo B,Wu H

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:Recent evidence cautions against the use of non-selective beta-blockers (NSBB) in patients with refractory ascites or spontaneous bacterial peritonitis while other data suggests a survival benefit in patients with advanced liver disease. The aim of this study was to describe the use and impact of NSBB in pat...

journal_title：BMC gastroenterology

authors： Ngwa T,Orman E,Gomez EV,Vuppalanchi R,Kubal C,Chalasani N,Ghabril M

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:A large-scale Japanese study showed that low skeletal muscle index (SMI) and intramuscular fat (IMF) deposition are associated with hepatocellular carcinoma (HCC) survival. Here, we evaluated the effects of SMI and IMF on the survival of Indonesian HCC patients, whose characteristics differ from those of Jap...

journal_title：BMC gastroenterology

authors： Mardian Y,Yano Y,Ratnasari N,Choridah L,Wasityastuti W,Setyawan NH,Hayashi Y

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Endoscopic nasobiliary drainage (ENBD) is widely used for biliary decompression in patients with biliary disease. However, it is difficult to reposition a nasobiliary catheter from the mouth to nostril. We developed a new device, which has a curved flexible loop and bar-handle, for repositioning of ENBD cath...

journal_title：BMC gastroenterology

authors： Choi SJ,Lee JM,Choi HS,Kim ES,Keum B,Seo YS,Jeen YT,Lee HS,Chun HJ,Um SH,Kim CD,Oh CH

更新日期：2019-12-21 00:00:00

abstract：BACKGROUND:Capsule endoscopy (CE) is the preferred diagnostic test of choice in the investigation of obscure gastrointestinal bleeding (OGIB). Although, a conservative strategy is recommended in the short-term, for cases with a negative result from CE, the impact of CE on long-term re-bleeding still remains unclear. He...

journal_title：BMC gastroenterology

authors： Wetwittayakhlang P,Wonglhow J,Netinatsunton N,Chamroonkul N,Piratvisuth T

更新日期：2019-12-16 00:00:00

abstract：PURPOSE:To determine the indications for adjuvant chemotherapy (AC) in patients with stage IIa gastric cancer (T3N0M0 and T1N2M0) according to the 7th American Joint Committee on Cancer (AJCC). METHODS:A total of 1593 patients with T3N0M0 or T1N2M0 stage gastric cancer were identified from the Surveillance, Epidemiolo...

journal_title：BMC gastroenterology

authors： Huang ZN,Desiderio J,Chen QY,Zheng CH,Li P,Xie JW,Wang JB,Lin JX,Lu J,Cao LL,Lin M,Tu RH,Lin JL,Zheng HL,Huang CM

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND:This case seeks to highlight to endoscopists a rare benign disorder that may be encountered during endoscopy. Clinicians may be tempted to biopsy, which could lead to a catastrophic gastrointestinal haemorrhage. CASE PRESENTATION:A 66-year-old asymptomatic Caucasian male was referred for colonoscopy with a ...

journal_title：BMC gastroenterology

authors： Abeysekera KWM,Pearl DS,Burn P,Lowe A

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Only a paucity of large-scale perspective and cross-sectional studies on H. pylori infection in China have been published. The purpose of this study was to investigate the prevalence and risk factors for H. pylori infection among residents of Jidong community located in Hebei Province of China. METHODS:A pe...

journal_title：BMC gastroenterology

authors： Wang W,Jiang W,Zhu S,Sun X,Li P,Liu K,Liu H,Gu J,Zhang S

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:A validated histopathological tool to precisely evaluate bowel fibrosis in patients with Crohn's disease is lacking. We attempted to establish a new index to quantify the severity of bowel fibrosis in patients with Crohn's disease-associated fibrostenosis. METHODS:We analyzed the histopathological data of 3...

journal_title：BMC gastroenterology

authors： Li XH,Fang ZN,Guan TM,Lin JJ,Sun CH,Huang SY,Mao R,Lu BL,Cao QH,Feng ST,Li ZP

更新日期：2019-11-11 00:00:00

abstract：BACKGROUND:The economic burden of ulcerative colitis (UC), specifically related to indirect costs, is not extensively documented. Understanding and quantifying it is required by health care decision makers. AIM:To assess the impact of indirect costs of UC in observation studies. METHOD:A systematic literature search ...

journal_title：BMC gastroenterology

authors： Constantin J,Atanasov P,Wirth D,Borsi A

更新日期：2019-11-09 00:00:00

abstract：BACKGROUND:Haemolytic uraemic syndrome is a rarely seen in adults often leading to critical illness. This case highlights how difficult it can be to establish a diagnosis and treat when a patient presents with bloody diarrhoea. CASE PRESENTATION:A 17-year-old Iraqi man presented to the emergency department with abdomi...

journal_title：BMC gastroenterology

authors： Radhakrishnan ST,Ruban A,Uthayakumar AK,Cohen P,Levy J,Teare J

更新日期：2019-08-28 00:00:00

abstract：BACKGROUND:Microcirculatory disturbance is an important factor in the pathogenesis of Inflammatory Bowel Disease (IBD) but there have been few studies in this field. Confocal Laser Endomicroscopy (CLE) has been used over the last 10 years and has made it possible to explore the changes in microcirculation of the coloni...

journal_title：BMC gastroenterology

authors： Tian Y,Zheng Y,Teng G,Li J,Wang H

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The assessment of residual gastric volume is common practice in critical care units. However, the effects and safety of discarding or returning gastric aspirates remain uncertain. Therefore, we aimed to evaluate the role of discarding or returning gastric aspirates on the gastric residual volumes in critical...

journal_title：BMC gastroenterology

authors： Wen Z,Xie A,Peng M,Bian L,Wei L,Li M

更新日期：2019-06-28 00:00:00

abstract：BACKGROUND:Studies on Epstein-Barr virus (EBV) have focused mostly on neoplastic disease. Few studies have considered immunocompetent patients who are not severely immunocompromised. Liver cirrhosis is associated with various levels of immune dysfunction. In the current study, we determined EBV infection rates, the inf...

journal_title：BMC gastroenterology

authors： Hu J,Zhang X,Yu G,Cai H,Gu J,Hu M,Xiang D,Lian J,Yu L,Jia H,Zhang Y,Yang Y

更新日期：2019-06-18 00:00:00

abstract：BACKGROUND:Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm that originates from follicular dendritic cells in lymphoid tissue while paraneoplastic pemphigus (PNP) is an autoimmune blistering disease associated with neoplasms. Pancreatic FDCS associated with PNP and myasthenia gravis (MG) is even rarer and h...

journal_title：BMC gastroenterology

authors： Lu T,Song B,Pu H,Li X,Chen Q,Yang C

更新日期：2019-06-14 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is commonly associated with a disturbance of glucose metabolism. However, there have been conflicting reports on whether the clearance of the HCV may be followed by changes of serum blood glucose and insulin resistance. The aim of the present study was to evaluate the impact...

journal_title：BMC gastroenterology

authors： Li Y,Wang X,Yu G,Sun H,Lv J,Chi X,Wu R,Gao X,Niu J

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:Bicyclol, the most commonly-used liver hepatoprotective drug in China, is often selected to control disease progression in CHB patients who refuse anti-viral treatment. However, data on histological changes after bicyclol treatment in these patients are scarce. Therefore, this study has been conducted to fin...

journal_title：BMC gastroenterology

authors： Chi X,Xiao H,Shi M,Cai G,Xie Y,Jiang J,Tian G,Wu S,Zhang C,Zhao P,Chen J

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:Pegylated interferon (PEG-IFN) alfa-2b is recommended for chronic hepatitis B (CHB). We aimed to investigate the sustainability of off-treatment responses among Chinese HBeAg-positive CHB patients treated with PEG-IFN alfa-2b from a randomized trial. METHODS:Eligible Chinese patients (n = 322) were followed...

journal_title：BMC gastroenterology

authors： Sun J,Ding H,Chen G,Wang G,Wei L,Zhang J,Xie Q,Wan M,Tang H,Chen S,Gao Z,Wang Y,Zhang D,Huang W,Sheng J,Ning Q,Yang D,Lu J,Pan C,Yang Y,Wang J,Sun C,Wang Q,Hou J

更新日期：2019-05-02 00:00:00

abstract：BACKGROUND:Vitamin K deficiency results in serious coagulation dysfunction, but hemorrhagic shock is rare. Herein, we describe a case of vitamin K deficiency and abnormality in the path of the intercostal artery, the combination of which led to hemorrhagic shock. CASE PRESENTATION:An 83-year-old woman was hospitalized...

journal_title：BMC gastroenterology

authors： Itagaki H,Hagino T

更新日期：2019-04-18 00:00:00

abstract：BACKGROUND:CMUSE is a rare disease whose diagnosis remains difficult because the lesion is confined to the small bowel. CASE PRESENTATION:Here, we present a case of 43-year-old female patient suffered chronic abdominal pain for 20 years, and finally diagnosed with CMUSE. Capsule endoscopy was performed when general en...

journal_title：BMC gastroenterology

authors： Tao EW,Zou TH,Wang YF,Tang JT,Chen YX,Gao QY

更新日期：2019-04-03 00:00:00

abstract：BACKGROUND:Hepatic expression of Sonic Hedgehog (SHH) is associated with Non-alcoholic fatty liver disease (NAFLD) and development of Non-alcoholic steatohepatitis (NASH). Hepatic SHH detection increases with the diagnosis of NASH. This pilot study was designed to confirm that staining for SHH is useful in NASH diagnos...

journal_title：BMC gastroenterology

authors： Estep M,Mehta R,Bratthauer G,Alaparthi L,Monge F,Ali S,Abdelatif D,Younoszai Z,Stepanova M,Goodman ZD,Younossi ZM

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) is a chronic complex disease of the gastrointestinal tract. Patients with IBD can experience a wide range of symptoms, but the pathophysiological mechanisms that cause these individual differences in clinical presentation remain largely unknown. In consequence, IBD is current...

journal_title：BMC gastroenterology

authors： Imhann F,Van der Velde KJ,Barbieri R,Alberts R,Voskuil MD,Vich Vila A,Collij V,Spekhorst LM,Van der Sloot KWJ,Peters V,Van Dullemen HM,Visschedijk MC,Festen EAM,Swertz MA,Dijkstra G,Weersma RK

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:This study investigated the relationship between liver stiffness and carotid artery elasticity in patients with chronic viral hepatitis. We used an acoustic radiation force impulse (ARFI) technique to measure stiffness, and a radio frequency (RF) vascular quantitative ultrasound technique to measure changes ...

journal_title：BMC gastroenterology

authors： Li JH,Zhu N,Min YB,Shi XZ,Duan YY,Yang YL

更新日期：2018-12-05 00:00:00

abstract：BACKGROUND:Hepatic arterioportal shunt (A-P shunt) is defined as the direct blood flow established between hepatic artery and portal venous system; it is frequently observed in patients with hepatocellular carcinoma (HCC). Clinically, it is important to diagnose HCC associated A-P shunts, as it may impact the treatment...

journal_title：BMC gastroenterology

authors： Wu H,Zhao W,Zhang J,Han J,Liu S

更新日期：2018-11-12 00:00:00

abstract：BACKGROUND:The elderly population presents higher morbidity of H. pylori associated diseases in proximal stomach. The specific pathogenesis and mechanism have not been clearly addressed. The gastric environment for H. pylori colonization is dynamic with increasing age. The aim of present study is to investigate the cor...

journal_title：BMC gastroenterology

authors： Shi H,Xiong H,Qian W,Lin R

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND:Transarterial chemoembolization (TACE) is the recommended treatment for hepatocellular carcinoma (HCC) patients at Barcelona Clinic Liver Cancer (BCLC) B-stage, whereas sorafenib is an orally administered small molecule target drug for BCLC C-stage. This updated systemic review and meta-analysis focuses on i...

journal_title：BMC gastroenterology

authors： Li L,Zhao W,Wang M,Hu J,Wang E,Zhao Y,Liu L

更新日期：2018-09-04 00:00:00

abstract：BACKGROUND:The use of immune-checkpoint inhibitors in cancer treatment has become increasingly common, resulting in an increase in the incidence of related side effects. Diarrhoea and colitis have been previously documented as gastrointestinal tract-related side effects of immune-checkpoint inhibitors. Although PD-1/PD...

journal_title：BMC gastroenterology

authors： Yamauchi R,Araki T,Mitsuyama K,Tokito T,Ishii H,Yoshioka S,Kuwaki K,Mori A,Yoshimura T,Tsuruta O,Torimura T

更新日期：2018-08-31 00:00:00

abstract：BACKGROUND:A variety of extra-intestinal manifestations (EIMs), including hepatobiliary complications, are associated with inflammatory bowel disease (IBD). Mesenchymal stem cells (MSCs) have been shown to play a potential role in the therapy of IBD. This study was designed to investigate the effect and mechanism of MS...

journal_title：BMC gastroenterology

authors： Niu GC,Liu L,Zheng L,Zhang H,Shih DQ,Zhang X

更新日期：2018-08-13 00:00:00

abstract：BACKGROUND:The mortality due to hemorrhage of esophageal varices (EV) is still high. The predominant cause for EV is liver cirrhosis, which has a high prevalence in Western Europe. Therefore, non-invasive screening markers for the presence of EV are of interest. Here, we aim to investigate whether non-inflammatory gall...

journal_title：BMC gastroenterology

authors： Tsaknakis B,Masri R,Amanzada A,Petzold G,Ellenrieder V,Neesse A,Kunsch S

更新日期：2018-08-02 00:00:00

abstract：BACKGROUND:Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC). Nonetheless, the relevance of faecal calprotectin (FC) measurement during granulomonocytapheresis (GMA) for UC has not yet been ...

journal_title：BMC gastroenterology

authors： Shimoyama T,Yamamoto T,Umegae S,Matsumoto K

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Stress is a common contributing factor for irritable bowel syndrome (IBS). This study was to evaluate the efficacy of the centralized health education program in improving the quality of life (QOL) of middle school students with IBS who experienced the Wenchuan earthquake on May 12, 2008. METHODS:A multi-ce...

journal_title：BMC gastroenterology

authors： Zheng SC,Gong H,Wang YP,Zhang Q,Wang LL,Liao XF,He DW,Wu J

更新日期：2018-07-27 00:00:00

abstract：BACKGROUND:Patients with familial adenomatous polyposis (FAP) frequently undergo colectomy to reduce the 70 to 90% lifetime risk of colorectal cancer. After risk-reducing colectomy, duodenal cancer and complications from duodenal surgeries are the main cause of morbidity. Our objective was to prospectively describe the...

journal_title：BMC gastroenterology

authors： Sample DC,Samadder NJ,Pappas LM,Boucher KM,Samowitz WS,Berry T,Westover M,Nathan D,Kanth P,Byrne KR,Burt RW,Neklason DW

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is mutually and bidirectionally linked with metabolic syndrome (MetS) of which it is both the cause and the consequences. Worldwide, 6.3 to 33% of the general populations are estimated to suffer from the disease with even higher prevalence in the group sharing metabo...

journal_title：BMC gastroenterology

authors： Pardhe BD,Shakya S,Bhetwal A,Mathias J,Khanal PR,Pandit R,Shakya J,Joshi HO,Marahatta SB

更新日期：2018-07-06 00:00:00

abstract：BACKGROUND:Acute pancreatitis (AP) is associated with considerable morbidity and mortality. Current severity scores include multiple variables and some of them are only complete within 48 h of admission. Red cell distribution width (RDW) is a simple and routine parameter that seems to be related to inflammatory status....

journal_title：BMC gastroenterology

authors： Gravito-Soares M,Gravito-Soares E,Gomes D,Almeida N,Tomé L

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:The emergence of multidrug-resistant (MDR) Escherichia coli (E. coli), particularly E. coli sequence type ST131, is becoming a global concern. Commensal bacteria, an important reservoir of antibiotic resistance genes, facilitate the spread of such genes to pathogenic bacterial strains. The objective of the s...

journal_title：BMC gastroenterology

authors： Huang IF,Lee WY,Wang JL,Hung CH,Hu HH,Hung WY,Hung YJ,Chen WC,Shen YT,Cheng MF

更新日期：2018-06-15 00:00:00